C beam: Monte Carlo simulations and experiment
نویسندگان
چکیده
Charge particle therapy with 12 C ions has the advantage of an enhancement in physical dose distribution due to the Bragg Peak (BP) related to higher Relative Biological Effectiveness (RBE) with respect to X-ray radiotherapy and proton therapy (2.5 for 12 C ions and 1.1 for protons) [1], [2]. The RBE of a 12 C therapeutic beam changes dramatically with depth, especially towards the end of the Spread Out Bragg Peak (SOBP), due to very high Linear Energy Transfer (LET) of the 12 C ions in this region. Additional complexity in the determination of the RBE is associated with the nuclear fragmentation process which leads to the production of lighter charged ions, with lower LET, and neutrons. Therefore, it is important to derive the RBE as well as study the fragments contribution of a therapeutic 12 C beam at the BP and SOBP.
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